HyperLink   TIGER: Tiled iterative genome assembler
Publication Year:
  Xiao-Long Wu, Yun Heo, Izzat El Hajj, Wen-mei Hwu, Deming Chen, Jian Ma
  Journal of BMC Bioinformatics, 2012

With the cost reduction of the next-generation sequencing (NGS) technologies, genomics has provided us with an unprecedented opportunity to understand fundamental questions in biology and elucidate human diseases. De novo genome assembly is one of the most important steps to reconstruct the sequenced genome. However, most de novo assemblers require enormous amount of computational resource, which is not accessible for most research groups and medical personnel.