Functionality and performance of EPIC architectural features depend on extensive compiler support. Predication, one of these features, promises to reduce control flow overhead and to enhance optimization, provided that compilers can utilize it effectively. Previous work has established the need for accurate, direct predicate analysis and has demonstrated a few useful techniques, but has not provided an efficient, general framework. This paper presents the Predicate Analysis System (PAS), which maps knowledge of predicate and condition relations in general control flow onto a convenient logical substrate, the reduced ordered binary decision diagram. PAS is the first such framework to demonstrate direct, accurate, and efficient analysis of arbitrary condition and predicate define networks in arbitrary control flow.